Grounded in a 2025 randomized trial of open-label placebo for PMS
4.8 / 5 from 6,700+ verified reviews
Clinician-reviewed protocol
100% natural & vegan gummies
Honest open-label placebo
Free shipping on every order
90-day money-back guarantee

OLP Treatment N°4 · 30 gummies

The 14-Day PMS Protocol

★★★★★4.8 / 5 6,700+ verified reviews
  • An honest, open-label placebo — no hormones, no prescription, no side-effects.
  • Eases the mood, cramping and irritability that crest in the luteal phase.
  • Run it across the back half of your cycle, when symptoms peak.
  • 30 natural, 100% vegan gummies 14-day supply
  • 14-day accountability tracker & ritual cards
  • Guided Copables app — one short lesson a day
  • Free shipping & 90-day money-back guarantee
Pre-order now $48

You won't be charged until your order ships. Cancel any time before dispatch.

100% natural
& vegan
Honest, open
label
Pause or cancel
any time
14days

The ritual is the medicine. Two gummies and a two-minute app check-in a day retrain the hormonal-mood conversation. Consistency is the whole game.

Clinician-reviewed protocol

Built on peer-reviewed open-label placebo research. See the evidence →

01 The protocol

Why the 14-Day Protocol works better.

The Copables kit — gummies, tracker and app

Honest by design

An open-label placebo. We tell you exactly what it is — and it works anyway.

Conditioned response

A lifetime of "take medicine → feel better" trains a real, physical reflex.

Symptom-loop reset

The daily ritual interrupts the worry-amplifies-symptoms feedback loop.

Drug-free

No prescription, no elimination diet, no side-effect roulette to manage.

Guided every day

The app turns the science into one short, plain-English lesson a day.

Measurable

Validated symptom tracking shows what changes — week over week.

★★★★★

"The week before my period used to flatten me."

— Nadia V.
100% natural & vegan Honest open-label Independently reviewed Cancel any time 90-day guarantee

02 The evidence

A gentler luteal phase, by design.

In a 2025 randomized controlled trial, an honest placebo produced a 79% reduction in PMS symptoms — one of the largest open-label-placebo effects yet recorded.

Copables turns that into a cycle-timed protocol: an honest pill, a daily ritual, and a body already wired to respond to expectation and care.

Read what 6,700+ members say
Figure 1 · PubMed 2010 — 2024
PubMed Publications · Year
300200100020102012201420162018202020222024Kaptchuk et al., 2010Seminal Harvard OLP study (IBS)272PUBS · 2024
Annual OLP publications 3 → 272 · ~90× in 14 yrs

03 Over time

How the protocol changes your weeks.

  • Two gummies a day, the tracker card, the app check-in
  • Begin in the back half of your cycle, as symptoms build
  • The brain re-learns the "care → relief" cue
  • Mood swings arrive with less force
  • Cramping and bloating feel more manageable
  • Irritability and overwhelm have less fuel
  • Symptom tracking shows the trend, cycle over cycle
  • The ritual becomes automatic, not effortful
  • Many members re-run it each luteal phase
The Copables protocol range

Backed by experts

The most underused tool in medicine — finally usable at home.

"For decades the open-label placebo effect has been one of the most striking findings in clinical research, and one of the least applied. Turning it into a structured, honest protocol people can actually run is exactly the kind of work the field has needed."
Dr. Priya Raman, PhDResearcher in mind–body medicine · advising Copables

04 What's inside

Why our protocol works better.

We don't sell another supplement to swallow and forget. Every part of the box is built to trigger the brain's own pharmacy — honestly, and on a schedule.

Start your protocol

Honest gummy

An open-label placebo. The label tells the truth — that’s the point.

Conditioned cue

A lifetime of "pill → relief" trains a measurable, physical reflex.

Loop reset

The daily ritual interrupts the worry-amplifies-symptoms cycle.

Mind–body axis

Targets the miscommunication, not a defect — a functional, treatable loop.

Ritual cards

A 14-day deck so the habit is impossible to forget.

Guided app

One short, plain-English lesson and check-in a day.

06 Customer reviews

4.8/5
★★★★★
6,700+ verified reviews
5 ★84%
4 ★11%
3 ★3%
2 ★1%
1 ★1%
NV
Nadia V.
✓ Verified member
Dec 4, 2025
★★★★★

My luteal week is finally livable

The week before my period used to flatten me. Two cycles on the protocol and the crash is a slope, not a cliff. I know how it works and I still find it a little magic.

BR
Bea R.
✓ Verified member
Nov 19, 2025
★★★★★

Honest beats hormones, for me

I didn’t want another pill with a side-effect list. This is inert and they say so. The mood swings lost their edge by the second cycle. The tracker made it easy to time.

CM
Cleo M.
✓ Verified member
Nov 1, 2025
★★★★★

The ritual gave me agency

Doing something kind and structured every day in my luteal phase changed the whole experience. The cramps are easier, but honestly the calmer mood is the bigger win.

DA
Dani A.
✓ Verified member
Oct 11, 2025
★★★★☆

Real help, not a miracle

Bloating and irritability both down a notch. Not zero — but enough that the week stopped derailing my life. Easy to just try with the guarantee.

FO
Fern O.
✓ Verified member
Sep 24, 2025
★★★★★

I stopped dreading the back half

Spent the first cycle waiting for the catch. There isn’t one. An honest ritual, timed to my cycle, and my body got the memo. Re-ordered already.

Questions, answered.

Everything about the protocol, the science and the guarantee. Still stuck? A real human answers at care@copables.com.

The product

OLP Treatment N°4: 30 natural, 100% vegan gummies (a 14-day supply at two a day), a 14-day accountability tracker, the ritual cards, the "Mind Over Medicine" welcome guide, and access to the guided Copables app.
Start in the back half of your cycle — the luteal phase — when PMS symptoms typically build, and run the 14 days through your period. The app helps you time it, and you re-run it each cycle.

Results & buying

Yes, and we tell you upfront. A 2025 randomized trial recorded a 79% reduction in PMS symptoms from an honest placebo. Your body responds to ritual, conditioning and expectation whether or not you’re "fooled." Backed by a 90-day money-back guarantee.
You save 15% and your next cycle ships automatically so you never break the habit. Pause, skip or cancel any time from your account — no emails, no fuss.

Safety

The gummies are inert, natural and vegan — there are no active drug interactions. That said, Copables isn’t a substitute for medical advice; keep taking anything your doctor prescribed and check with them if you have a serious condition.
90 DAY

OUR PROMISE TO YOU

Run the 14 days. If your pms isn't calmer, it's free.

We've helped over 6700+ people live easier with PMS — but we know it won't work for everyone. So every protocol is backed by a full 90-day money-back guarantee.

"We built this for the people who've been told it's 'just in your head,' as if that makes it less real. It isn't. The hormonal-mood link is real — and so is the relief."
— Theo Marsh, Co-founder of Copables
1
Finish the 14 days

Complete the protocol, ritual and all.

2
Email us once

No forms, no return shipping, no hold music.

3
Get a full refund

Every cent back, any time within 90 days.

PMS ProtocolPre-order · $48
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