Open-label placebos
Placebos can help even when you know.
Five evidence-based protocols that harness your brain's own pharmacy to improve your condition.

Designed using research from the world's leading institutions

01 The problem
Where conventional care runs out.
You've tried the standard path. Tests come back clear. Medication takes the edge off, but never quite resolves it. For millions, the diagnosis is one of exclusion — and the cycle continues.
Treated, not resolved.
Medication manages the symptom. On first-line drugs, most patients still miss the responder threshold — so you try the next thing, and the next.
Neural, not chemical.
Your brain and body are in constant conversation. Most drugs don't speak that language — they target chemistry, not the signalling that creates symptoms in the first place.
A different substrate.
Your nervous system responds to expectation, ritual and belief. It always has — Copables is built on that substrate.
02 Inside-out
Your brain has its own pharmacy. It just needs to be unlocked.
Studies have shown that non-deceptive placebos can cause your brain to produce the very same symptom-relieving chemicals present in real pharmacology.
See the Science →
03 A new field
Placebos are one of the most underutilized tools in modern medicine.
Open Label Placebos are an emerging field of research whose benefits lie locked away in research labs. Until now.
View 272 OLP publications in PubMed04 Analog · Digital

Copables is a 14-day protocol that leverages the power of the analog world and the digital world.
A physical kit arrives at your door — capsules, ritual cards and a welcome guide. Scan each day's card with the app for personalised CBT coaching and validated symptom tracking you can measure week over week.
Start your protocol →Receive your kit
Capsules, ritual cards and a welcome guide, shipped to your door.
Begin the ritual
Take your capsules and follow the day's card prompt — ten minutes a day.
Scan for coaching
Scan each card with the app for personalised CBT exercises.
Track outcomes
Validated symptom tracking shows what changes, week over week.
05 The promise
No meds. No huge costs. No doctor's office.
A clinically-grounded protocol you run from home in fourteen days — built on the same neurochemistry your prescriptions rely on.
Copables is an anagram of the word "placebos."

06 What members say
I noticed a real
difference in just the
first week.
"I was sceptical at first, but the ritual made me actually look forward to taking the capsule each morning. By day 10 my bloating had noticeably reduced."
"The app coaching is genuinely useful. It reframed how I think about my symptoms — not as something to fight, but as something my brain can learn to dial down."
"What surprised me most was how the ritual cards became a genuine anchor in my day. I wasn't just taking a placebo — I was building a habit that shifted my outlook."
07 The protocols
Learn more about our Protocols.
Each protocol is purpose-built for one condition on the same evidence-based foundation — the same 14-day system, shaped to you.
A 14-day gut–brain protocol. Harvard RCT validated.
Daily ritual plus CBT to settle the body's alarm.
Rebalancing low mood — without medication.
Hormonal symptom management, tuned to your cycle.
Energy regulation through a nervous-system reset.
Coming soon
The pipeline is expanding. Sign up to be notified.
Not sure which protocol fits? Take the 2-minute assessment.
Find your protocol →